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The plants are immersed in water and when they swell, inoculated with bacteria which hydrolyze pectic substances of the cell walls and separate the fibres. However, early metagenomic studies revealed that there are probably large groups of microorganisms in many environments that cannot be cultured and thus cannot be sequenced. There is also a combined clinical classification, which combines factors such as age, risk factors for certain microorganisms, the presence of underlying lung disease or systemic disease and whether the person has recently been hospitalized. Individuals and groups can employ a safe deposit service for their own cell cultures, providing a secure back-up for valuable biomaterials if required. Some protists reproduce sexually using gametes, while others reproduce asexually by binary fission.

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